Resident Population in Macon County, MO was 15.16100 Thous. of Persons in January of 2023, according to the United States Federal Reserve. Historically, Resident Population in Macon County, MO reached a record high of 16.72400 in January of 1981 and a record low of 15.04900 in January of 2022. Trading Economics provides the current actual value, an historical data chart and related indicators for Resident Population in Macon County, MO - last updated from the United States Federal Reserve on May of 2024.